Overweight & Obesity

Bariatric surgery improves adipose tissue function

(HealthDay)—Bariatric surgery is associated with improvements in adipose tissue function, some of which are independent of weight loss, according to research published online June 8 in Obesity Reviews.

Oncology & Cancer

CT-based calculations improve accuracy of PET for cancer patients

Cancer patients often experience significant fluctuations in weight and lean body mass (LBM). Neglecting to account for these changes can prevent clinicians from obtaining precise data from molecular imaging, but a new method ...

Medical research

Fat tissue shows a robust circadian rhythm in a dish

In humans, glucose tolerance varies with time of day, but the mechanism responsible for the variation in insulin sensitivity throughout the day is unclear. In a recent study in The Journal of the Federation of American Societies ...

Diabetes

Epigenomic alterations contribute to obesity-associated diabetes

Obesity is a risk factor for developing type 2 diabetes, yet not all obese humans develop the disease. In a new study, researchers from the Karolinska Institutet in Sweden and from the Institute of Health and Medical Research ...

Diabetes

Metformin combats adipose tissue expansion via AMPK

(HealthDay)—AMPK activation by metformin is associated with inhibition of interstitial fibrosis and suppression of transforming growth factor β-1 (TGF-β1), according to a study published online May 13 in Diabetes.

Diabetes

Changes in adipose tissue with lack of insulin, IGF-1 receptors

(HealthDay)—Mice lacking either the insulin receptor (IR), insulin-like growth factor 1 receptor (IGF1R), or both have disruptions in white and brown adipose tissue (WAT and BAT) formation, with an almost complete absence ...

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