Diabetes

Metformin combats adipose tissue expansion via AMPK

(HealthDay)—AMPK activation by metformin is associated with inhibition of interstitial fibrosis and suppression of transforming growth factor β-1 (TGF-β1), according to a study published online May 13 in Diabetes.

Medical research

Cholesterol-lowering drugs reduce brown adipose tissue

ETH Zurich scientists have shown that statins, one of the most commonly prescribed classes of pharmaceuticals, reduce beneficial brown adipose tissue. But this is no reason to demonise these drugs, the researchers insist.

Medical research

Could coffee be the secret to fighting obesity?

Scientists from the University of Nottingham have discovered that drinking a cup of coffee can stimulate 'brown fat', the body's own fat-fighting defenses, which could be the key to tackling obesity and diabetes.

Immunology

Innate immune responses to high-fat diets lead to obesity

Why is eating a high fat diet a recipe for obesity? According to a new study from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan, the answer involves the activity of a specific type of immune cell that lives ...

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