Oncology & Cancer

A strategy for combating drug-resistant cancers

Many cancer therapies function by activating proteins like Caspase-3 (CASP3) that promote cell death. Several forms of cancer develop resistance to these drugs by down regulating CASP3 through an unknown mechanism. In the ...

Medications

US court rules to protect generic drug makers

Manufacturers of generic drugs cannot be sued for adverse side effects caused by products that they did not themselves design, the US Supreme Court ruled on Monday.

Oncology & Cancer

New prostate cancer test improves risk assessment

(Medical Xpress)—A new genomic test for prostate cancer can help predict whether men are more likely to harbor an aggressive form of the disease, according to a new UC San Francisco study. The test, which improves risk ...

Psychology & Psychiatry

The hunt for a successor to lithium for bipolar disorder

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body—with an eye ...

Cardiology

ACC: Niacin/Laropiprant no benefit in vascular disease

(HealthDay)—For patients with preexisting occlusive vascular disease, the combination of niacin and the anti-flushing agent laropiprant provides no benefit and is associated with an increase in serious side effects, according ...

Oncology & Cancer

Virus shows promise as prostate cancer treatment

A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of ...

Arthritis & Rheumatism

Rheumatism drug also effective at half dose

The treatment of moderately active rheumatoid arthritis with the tumour necrosis factor inhibitor Etanercept achieves excellent success in more than 80 per cent of patients. With this method, the success can be maintained ...

Oncology & Cancer

Spin and bias in published studies of breast cancer trials

Spin and bias exist in a high proportion of published studies of the outcomes and adverse side-effects of phase III clinical trials of breast cancer treatments, according to new research published in the cancer journal Annals ...

Diseases, Conditions, Syndromes

Hepatitis C treatment's side effects can now be studied in the lab

(Medical Xpress)—The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg Professor of ...

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