Inflammatory disorders

Sensor tracks cortisol levels in real time

Skoltech researchers have developed a prototype of a fluorescence-based sensor for continuous detection of cortisol concentrations in real time, which can help monitor various health conditions. The paper was published in ...

Cardiology

New weapon for inflammation

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

Medications

COVID-19: Dexamethasone discovery carries treatment implications

A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness. ...

Diabetes

More diabetic foot amputations seen during COVID-19 lockdown

(HealthDay)—Patients with diabetes admitted to a tertiary care center for diabetic foot ulceration (DFU) during the COVID-19 lockdown in Italy had a more than threefold risk for amputation versus patients seen in 2019, ...

Diseases, Conditions, Syndromes

Universal gut microbiome-derived signature predicts cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to ...

Diabetes

Addition of sotagliflozin for T1DM alters renal hemodynamics

(HealthDay)—Sotagliflozin (SOTA), a dual sodium-glucose cotransporter 1 inhibitor (SGLT1i) and SGLT2i, is associated with short- and long-term renal hemodynamic changes in patients with type 1 diabetes, according to a study ...

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Albumin

Albumin (Latin: albus, white) refers generally to any protein that is water soluble, which is moderately soluble in concentrated salt solutions, and experiences heat denaturation. They are commonly found in blood plasma, and are unique to other plasma proteins in that they are not glycosylated. Substances containing albumin, such as egg white, are called albuminoids.

A number of serum transport proteins are known to be evolutionarily related, including serum albumin, alpha-fetoprotein, vitamin D-binding protein and afamin.

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