Diseases, Conditions, Syndromes

Alkaline phosphatase, bilirubin predict outcomes in PBC

(HealthDay)—For patients with primary biliary cirrhosis (PBC), levels of alkaline phosphatase and bilirubin predict clinical outcome, according to a meta-analysis published in the December issue of Gastroenterology.

Biomedical technology

A 'sugar' coating for bone implants

Osteoporosis is a leading global health challenge. Besides its own adverse effects, it also impairs the function of bone implants—normally made of a metal called titanium (Ti). Because there is less bone than normal at ...

Diseases, Conditions, Syndromes

Steatosis in more than half of liver transplant recipients

(HealthDay)—Steatosis affects more than half of liver transplant (LT) recipients, although it is not associated with worse patient survival, according to a study published online April 5 in Liver Transplantation.

Medications

Drug approved to treat tenosynovial giant cell tumor

(HealthDay)—Turalio (pexidartinib) capsules have been approved to treat adults with symptomatic tenosynovial giant cell tumor (TGCT), the U.S. Food and Drug Administration announced.

Oncology & Cancer

Cabozantinib active in castration-resistant prostate cancer

(HealthDay)—The orally bioavailable tyrosine kinase inhibitor cabozantinib (XL184) has clinical activity in men with castration-resistant prostate cancer (CRPC), according to a study published online Nov. 19 in the Journal ...

Medical research

Biomarker monitors testosterone therapy for osteoporosis

That biomarker, an enzyme called alkaline phosphatase, can be checked through a test similar to a routine blood draw, making this type of screening preferable to the more expensive and invasive DEXA scan, which measures bone ...

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