The enzyme AMPK initiates a dizzying array of cellular activities, from breaking down worn-out cellular parts to turning on energy production. How does a single protein, activated by a single switch, fulfill so many different ...
Apr 16, 2015
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UT Southwestern Medical Center scientists have identified a new biomarker that could help identify patients who are more likely to respond to certain chemotherapies.
Feb 18, 2015
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Abnormal metabolism within the cells is a distinctive characteristic of cancer, but until now, the mechanism that causes cells to undergo this metabolic shift remained unknown.
Feb 11, 2015
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Stopping Australia's most commonly diagnosed cancer - prostate cancer - in its tracks is the goal of scientists around the world.
Sep 11, 2014
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UCLA biologists have identified a gene that can slow the aging process throughout the entire body when activated remotely in key organ systems.
Sep 8, 2014
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University of Alberta researchers are taking a closer look at how two metabolic pathways interact to increase the lifespan of cells with mitochondrial defects. Magnus Friis is the lead author of the study, which was published ...
Apr 11, 2014
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Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects ...
Apr 10, 2014
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The diabetes drug metformin is also being tested in numerous clinical trials for treating different cancers, and several studies point to its apparent activation of a molecular regulator of cell metabolism called AMPK to ...
Jan 13, 2014
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Researchers at the University of California, San Diego School of Medicine say that, while a prevailing theory suggests elevated cellular levels of glucose ultimately result in diabetic kidney disease, the truth may, in fact, ...
Oct 25, 2013
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Research from three Yale laboratories—in the fields of immunobiology, chemistry, and cardiology—could lead to new drugs to reduce complications during cardiac surgery or heart attacks. If they pan out in human trials, ...
Jul 24, 2013
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