Medications

Scientists discover key regulator of neuron function and survival

Scientists studying neuronal energy metabolism found evidence that the loss of an important energy regulator called AMPK in neural stem cells or glial cells called astrocytes causes neuronal death in laboratory rodents. They ...

Medical research

AMPK amplifies Huntington's disease

A new study describes how hyperactivation of AMP-activated protein kinase (AMPK) promotes neurodegeneration in Huntington's disease (HD). The article appears online on July 18, 2011, in The Journal of Cell Biology.

Medical research

Key enzyme plays roles as both friend and foe to cancer

A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of Illinois at Chicago ...

Medical research

Nutrients may reduce blood glucose levels

Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins. Scientists at Joslin Diabetes Center now have shown that one amino acid, alanine, ...

Oncology & Cancer

Cancer cell metabolism kills

Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply can be fatal ...

Medical research

Researchers examine metabolism in defective cells

University of Alberta researchers are taking a closer look at how two metabolic pathways interact to increase the lifespan of cells with mitochondrial defects. Magnus Friis is the lead author of the study, which was published ...

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