An analysis of human brain cells provides new evidence in support of the "amyloid hypothesis," the prevailing idea that Alzheimer's is caused by the accumulation of beta-amyloid proteins in the brain.
Mar 31, 2023
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The brain damage that characterizes Alzheimer's disease may originate in a form similar to that of infectious prion diseases such as bovine spongiform encephalopathy (mad cow) and Creutzfeldt-Jakob, according to newly published ...
Oct 4, 2011
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Losing the activity of a key ion channel in the brain may contribute to the buildup of a devastating and toxic protein responsible for the clumps of plaque that accumulate in Alzheimer's disease, a team of neurobiologists ...
Lysosomes, the "garbage disposal" systems of cells, are found in great abundance near the amyloid plaques in the brain that are a hallmark of Alzheimer's disease. Scientists have long assumed that their presence was helpful—that ...
Jun 30, 2015
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Around 80% of people with Down syndrome develop Alzheimer's disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer's disease ...
Aug 24, 2022
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A substance known as amyloid beta protein gets a lot of attention from scientists. Beta amyloid, as it's also called, is a normal brain protein found in everyone, but for an unknown reason it gunks up in the brains of patients ...
Jun 11, 2019
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Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer's disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly ...
May 29, 2020
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Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates—a telltale sign of Alzheimer's brain pathology—never ...
May 29, 2023
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Researchers have used a non-invasive method of observing how the process leading to Parkinson's disease takes place at the nanoscale, and identified the point in the process at which proteins in the brain become toxic, eventually ...
Mar 14, 2016
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The study, published May 29 in the open access Nature Publishing Group journal Scientific Reports, reveals a direct link between the main culprit of Alzheimer's disease and memory loss.
May 29, 2015
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