Diseases, Conditions, Syndromes

Amyloid formation may link Alzheimer disease and type 2 diabetes

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). However, little is ...

Alzheimer's disease & dementia

Mechanism in Alzheimer's-related memory loss identified

Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted ...

Medical research

A wrong molecular turn leads down the path to Type 2 diabetes

Computing resources at the U.S. Department of Energy's (DOE) Argonne National Laboratory have helped researchers better grasp how proteins misfold to create the tissue-damaging structures that lead to type 2 diabetes. The ...

Alzheimer's disease & dementia

Scientists reveal how beta-amyloid may cause Alzheimer's

Scientists at the Stanford University School of Medicine have shown how a protein fragment known as beta-amyloid, strongly implicated in Alzheimer's disease, begins destroying synapses before it clumps into plaques that lead ...

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