Alzheimer's disease & dementia

Healthy mitochondria could stop Alzheimer's

Alzheimer's disease is the most common form of dementia and neurodegeneration worldwide. A major hallmark of the disease is the accumulation of toxic plaques in the brain, formed by the abnormal aggregation of a protein called ...

Alzheimer's disease & dementia

Mechanism in Alzheimer's-related memory loss identified

Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted ...

Diseases, Conditions, Syndromes

Unravelling the mysteries around type 2 diabetes

For more than 30 years, scientists have been trying to unravel the mystery of how a key biological molecule self assembles into a rogue protein-like substance known as amyloid, which is thought to play a role in the development ...

Alzheimer's disease & dementia

Brain tissue inflammation is key to Alzheimer's disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School ...

Alzheimer's disease & dementia

Scientists reveal how beta-amyloid may cause Alzheimer's

Scientists at the Stanford University School of Medicine have shown how a protein fragment known as beta-amyloid, strongly implicated in Alzheimer's disease, begins destroying synapses before it clumps into plaques that lead ...

Diseases, Conditions, Syndromes

Amyloid formation may link Alzheimer disease and type 2 diabetes

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). However, little is ...

page 1 from 3