A research team led by the National Neuroscience Institute (NNI) has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer's disease. This discovery may help researchers ...
Apr 21, 2014
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An international team of researchers has discovered a new binding partner for amyloid precursor protein (APP)—a neurotransmitter called GABABR1a. In their paper published in the journal Science, the group describes their ...
New research published today in Alzheimer's & Dementia, the journal of the Alzheimer's Association could explain why neurons fail to communicate effectively in people with Alzheimer's disease (AD). The study conducted by ...
Jan 25, 2022
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Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry ...
Jan 3, 2012
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What if Alzheimer's disease left its mark on the embryo? Khadijeh Shabani and her colleagues from the Brain Development team led by Bassem Hassan (Inserm) at Paris Brain Institute show that the amyloid precursor protein (APP) ...
Jun 16, 2023
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Previous research has implicated fungi in chronic neurodegenerative conditions such as Alzheimer's disease, but there is limited understanding of how these common microbes could be involved in the development of these conditions.
Oct 16, 2023
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Blocking a transport pathway through the brain cells offers new prospects to prevent the development of Alzheimer's. Wim Annaert and colleagues of VIB and K.U. Leuven discovered that two main agents involved in the inception ...
Aug 22, 2011
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Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...
Aug 14, 2019
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Researchers have identified amyloid beta (Aβ) detected in blood to originate from peripheral tissues, and that the peptide acts on pancreaticβ-cells to suppress insulin secretion, thereby regulating blood glucose levels. ...
Mar 15, 2022
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Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific ...
May 16, 2018
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