Alzheimer's disease & dementia

Tiny worm mimics key genetic risk for Alzheimer's

Researchers at The University of Alabama have shown a tiny worm can replicate genetic causes of Alzheimer's disease, expanding the breadth of preclinical models for the disease.

Alzheimer's disease & dementia

'Lack of cleaning' in brain cells is central to Alzheimer's disease

An international research team with representation from the University of Copenhagen has created a better understanding of Alzheimer's. They have shown that the cleaning system of the brain cells, a process called mitophagy, ...

Alzheimer's disease & dementia

A new culprit of cognitive decline in Alzheimer's disease

It has long been known that patients with Alzheimer's disease have abnormalities in the vast network of blood vessels in the brain. Some of these alterations may also contribute to age-related cognitive decline in people ...

Neuroscience

Lifespan brain study adds possible clue in predicting Alzheimer's

New research from The University of Texas at Dallas suggests that periodic evaluation of changing amyloid levels in certain brain structures may offer an important clue into who may be on a trajectory toward Alzheimer's disease.

Alzheimer's disease & dementia

Neuronal cytoskeletons involved in Alzheimer's disease

A researcher at the UPV/EHU participated in a study describing the loss of dynamics and subsequent impairment of the dendritic spines in Alzheimer's disease. Dendritic spines are the compartments of neurons responsible for ...

Neuroscience

Unraveling the mysteries of multiple sclerosis

Leiden chemists discovered a new mechanism which might explain how multiple sclerosis shifts to a more severe form. Their findings contribute to unraveling the mysterious course of the disease. They have published their findings ...

Alzheimer's disease & dementia

Immune cell defect stimulates Alzheimer's

Defects in the gene TREM2 are linked to increased risk of Alzheimer's disease. The gene is required to activate immune cells called microglia in the brain, which help to eliminate the neurotoxic deposits that are typical ...

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Amyloid

Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. Abnormal accumulation of amyloid in organs may lead to amyloidosis, and may play a role in various neurodegenerative diseases.

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