Genetics

Viking DNA and the pitfalls of genetic ancestry tests

A middle-aged white man raises his sword to the skies and roars to the gods. The results of his genetic ancestry test have just arrived in his suburban mailbox. His eyes fill with tears as he learns that he is "0.012% Viking." ...

Genetics

Race, medicine and the future power of genetic ancestry

Writing in the New England Journal of Medicine that they "do not believe that ignoring race will reduce health disparities" but rather that "such an approach is a form of naive 'color blindness' that is more likely to perpetuate ...

Genetics

First multi-whole-genome study of IBD in African Americans

In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans. ...

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Ancestor

An ancestor is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth).

Two individuals have a genetic relationship if one is the ancestor of the other, or if they share a common ancestor. In evolutionary theory, species which share an evolutionary ancestor are said to be of common descent. However, this concept of ancestry does not apply to some bacteria and other organisms capable of horizontal gene transfer.

Assuming that all of an individual's ancestors are otherwise unrelated to each other, that individual has 2n ancestors in the nth generation before him and a total of about 2g+1 ancestors in the g generations before him. In practice, however, it is clear that the vast majority of ancestors of humans (and indeed any other species) are multiply related (see Pedigree collapse). Consider n = 40: the human species is more than 40 generations old, yet the number 240, approximately 1012 or one trillion, dwarfs the number of humans that have ever lived.

Ignoring the possibility of other inter-relationships (even distant ones) among ancestors, an individual has a total of 2046 ancestors up to the 10th generation, 1024 of which are 10th generation ancestors. With the same assumption, any given person has over a billion 30th generation ancestors (who lived roughly 1000 years ago) and this theoretical number increases past the estimated total population of the world in around AD 1000. (All of these ancestors will have contributed to one's autosomal DNA is concerned: this excludes Y-chromosomal DNA and mitochondrial DNA.)

Some cultures confer reverence to ancestors, both living and dead; in contrast, some more youth-oriented cultural contexts display less veneration of elders. In other cultural contexts, some people seek providence from their deceased ancestors; this practice is sometimes known as ancestor worship or, more accurately, ancestor veneration.

This text uses material from Wikipedia, licensed under CC BY-SA