Psychology & Psychiatry

Determined DNA hunt reveals schizophrenia clue

An 18-year study using the DNA of thousands of people in India has identified a new clue in the quest for causes of schizophrenia, and for potential treatments.

Genetics

Genomic collision may explain why many kidney transplants fail

A genomic collision could explain why many kidney transplants fail, even when donors and recipients are thought to be well-matched, according to a new study from researchers at Columbia University Vagelos College of Physicians ...

Diseases, Conditions, Syndromes

How the flu vaccine fails

Influenza is ubiquitous. Every fall, we line up to get our flu shots with the hope that we will be protected from the virus that infects 10 to 20 percent of people worldwide each year. But some years, the vaccine is less ...

Genetics

Researchers identify 'beauty spots' in the genome

Genes play a role in determining the beauty of a person's face, but that role varies with the person's sex, according to a new study by Qiongshi Lu and colleagues at the University of Wisconsin-Madison, published 4th April ...

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Ancestor

An ancestor is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth).

Two individuals have a genetic relationship if one is the ancestor of the other, or if they share a common ancestor. In evolutionary theory, species which share an evolutionary ancestor are said to be of common descent. However, this concept of ancestry does not apply to some bacteria and other organisms capable of horizontal gene transfer.

Assuming that all of an individual's ancestors are otherwise unrelated to each other, that individual has 2n ancestors in the nth generation before him and a total of about 2g+1 ancestors in the g generations before him. In practice, however, it is clear that the vast majority of ancestors of humans (and indeed any other species) are multiply related (see Pedigree collapse). Consider n = 40: the human species is more than 40 generations old, yet the number 240, approximately 1012 or one trillion, dwarfs the number of humans that have ever lived.

Ignoring the possibility of other inter-relationships (even distant ones) among ancestors, an individual has a total of 2046 ancestors up to the 10th generation, 1024 of which are 10th generation ancestors. With the same assumption, any given person has over a billion 30th generation ancestors (who lived roughly 1000 years ago) and this theoretical number increases past the estimated total population of the world in around AD 1000. (All of these ancestors will have contributed to one's autosomal DNA is concerned: this excludes Y-chromosomal DNA and mitochondrial DNA.)

Some cultures confer reverence to ancestors, both living and dead; in contrast, some more youth-oriented cultural contexts display less veneration of elders. In other cultural contexts, some people seek providence from their deceased ancestors; this practice is sometimes known as ancestor worship or, more accurately, ancestor veneration.

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