Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers at the University of Tokyo refer to their technique as the human ADLib system, short for autonomously diversifying ...
May 26, 2020
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A family of cancer suppressive proteins, known as TET proteins, help regulate gene activity via their influence on chromosomal architecture. However, until now it wasn't entirely clear how genes were activated by TET proteins ...
Apr 26, 2019
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A team of researchers with members affiliated with several institutions in Canada has found an association between children with a genetic disposition to type 1 diabetes (T1D) and anticommensal antibodies in their serum prior ...
Researchers have taken advantage of the benefits of DNA immunization over traditional protein-based immunization to elicit monoclonal antibodies (mAbs) against challenging targets in three species – mouse, rabbit, and human ...
Oct 22, 2018
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A new study comparing the effectiveness of individual ZMapp antibodies versus a cocktail of antibodies, administered to mice using recombinant adeno-associated virus (rAAV) delivery vectors, showed the ability to achieve ...
Mar 9, 2018
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Researchers from the Greehey Children's Cancer Research Institute at UT Health San Antonio co-authored a paper published Sept. 26 in Science Signaling that looks at the reliability of a common research tool to study RAS cancer ...
Oct 5, 2017
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New research has found that genetic differences in antibody genes alter individuals' susceptibility to rheumatic heart disease, a forgotten inflammatory heart condition – known as 'RHD' – that is rife in developing countries.
May 12, 2017
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Scientists at The Scripps Research Institute (TSRI) have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus. Their experiments under lab conditions show that these ...
Apr 10, 2017
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A new, long-term study examined the antibody response to natural infection with adeno-associated virus (AAV) in chimpanzees for the purpose of characterizing the broad-based immune responses that could reduce the effectiveness ...
Aug 11, 2016
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A new study in patients with the inherited metabolic disorder methylmalonic academia (MMA) found lower than expected levels of antibodies against the adeno-associated viral (AAV) vectors being developed for gene therapy to ...
Apr 5, 2016
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