A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody. Investigators ...
Mar 8, 2023
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111
As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially omicron, have developed ways to evade the antibodies we make in response ...
Aug 11, 2022
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170
Researchers at the University of Toronto have discovered that an overlooked gene plays a major role in the development of antibodies, which help the immune system recognize and fight viruses including SARS-CoV-2, bacteria ...
Nov 24, 2021
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266
A study coordinated by Luís Graça, principal investigator at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Professor at the Faculty of Medicine of the University of Lisbon (FMUL) used lymph ...
May 28, 2021
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55
Immunotherapies have transformed the treatment of several types of cancer over the last decade. Yet they focus on reactivating one arm of the immune system: cytotoxic T cells, which sniff out and kill tumor cells.
Nov 19, 2020
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59
A family of cancer suppressive proteins, known as TET proteins, help regulate gene activity via their influence on chromosomal architecture. However, until now it wasn't entirely clear how genes were activated by TET proteins ...
Apr 26, 2019
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62
A team of researchers with members affiliated with several institutions in Canada has found an association between children with a genetic disposition to type 1 diabetes (T1D) and anticommensal antibodies in their serum prior ...
Researchers from the Greehey Children's Cancer Research Institute at UT Health San Antonio co-authored a paper published Sept. 26 in Science Signaling that looks at the reliability of a common research tool to study RAS cancer ...
Oct 5, 2017
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27
New research has found that genetic differences in antibody genes alter individuals' susceptibility to rheumatic heart disease, a forgotten inflammatory heart condition – known as 'RHD' – that is rife in developing countries.
May 12, 2017
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51
Scientists at The Scripps Research Institute (TSRI) have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus. Their experiments under lab conditions show that these ...
Apr 10, 2017
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