Novel immune checkpoints have applications for cancer, autoimmune disease treatment
The immune system is a complex balancing act; if it overreacts or underreacts to foreign molecules, there can be serious health consequences.
May 20, 2021
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The immune system is a complex balancing act; if it overreacts or underreacts to foreign molecules, there can be serious health consequences.
May 20, 2021
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Of the 198 new oncology drugs approved by the U.S. Food and Drug Administration (FDA) between 1998 and 2022, approximately 43% were precision oncology therapies, the use of which is guided by biomarker testing.
Oct 18, 2023
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A new research report published in the Journal of Leukocyte Biology shows how the bacteria known for causing gum disease—Porphyromonas gingivalis—manipulates the body's immune system to disable normal processes that would ...
Jan 3, 2013
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Scientists have for the first time revealed the structure surrounding important receptors in the brain's hippocampus, the seat of memory and learning.
May 12, 2021
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Young children who suffer from allergy to raw egg are being fed cake containing baked egg in a new study aimed at helping children to outgrow their allergy.
May 6, 2013
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Cancer Research UK scientists at the University of Southampton are seeing positive results in a pre-clinical trial that could bring treatments for a particular aggressive form of childhood cancer closer to reality.
Jul 11, 2013
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Wistar scientists and collaborators demonstrate for the first time that through engineering constructs, they can express DNA-encoded monoclonal antibodies (DMAbs) targeting CTLA-4, an important cancer checkpoint molecule ...
Oct 4, 2018
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Neural stem cells are the precursors of cells in the nervous system. As well as being crucial for early development, they are present throughout life, contributing to flexibility and repair of the nervous system. As such, ...
Oct 24, 2012
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Researchers from The Hospital for Sick Children (SickKids) recently decoded how human antibodies protect us from the malaria parasite, which kills more than 600,000 people worldwide annually. The CMCF facility at the Canadian ...
Nov 27, 2023
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Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain ...
Jan 8, 2014
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