Medications

New strategies reduce treatment failure in malaria by up to 81%

Artemisinin-based combination therapies (ACTs) are the globally-accepted first-line treatments for malaria—a mosquito-borne disease caused by the Plasmodium falciparum parasite that annually kills around 600,000 people, ...

Diseases, Conditions, Syndromes

Monoclonal antibody prevents malaria infection in African adults

One dose of an antibody drug safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa, a National Institutes of Health clinical trial has found. The antibody ...

Diseases, Conditions, Syndromes

Investigational malaria vaccine gives strong, lasting protection

Two U.S. Phase 1 clinical trials of a novel candidate malaria vaccine have found that the regimen conferred unprecedentedly high levels of durable protection when volunteers were later exposed to disease-causing malaria parasites. ...

Medications

Scientists design new drug compound to stop malaria in its tracks

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop ...

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