HIV & AIDS

Overcoming immune exhaustion from chronic HIV infection

Chronic HIV infection results in exhaustion of the immune system, a phenomenon characterized by dysfunctional HIV-specific killer T cells. The exhausted T cells display inhibitory proteins on their surface, and scientists ...

HIV & AIDS

IL-21 repairs immune function in primate model of HIV infection

Antiretroviral drugs can suppress HIV for years, but a residual inflammatory imbalance contributes to health problems in infected individuals who are infected with the virus. A novel combination treatment aimed at repairing ...

HIV & AIDS

Towards elimination of HIV reservoirs

Current antiretroviral therapy can keep HIV in check and prevent AIDS in the vast majority of treated patients. However, as it is unable to eliminate viral reservoirs and cure the infection, patients need to stay on the life-long ...

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