The major obstacle to curing HIV is a vast reservoir of "latent, replication-competent proviruses," which have infiltrated the very cells that help orchestrate the immune response.
Research led by the Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, has found a potentially better alternative to standard antiretroviral treatment for controlling HIV-1 ...
The infection of human immunology viruses (HIV) occurs by integrating its genome into infected cells to enter an inactive state of reversible latency that evades anti-retroviral therapy. The capacity to sequence such a provirus ...
Some people diagnosed with HIV are able to eradicate the virus without antiretroviral medications or even stem cell transplants, possessing the ability to naturally suppress the virus and achieve a medically verifiable cure.
Researchers at MIT and Brigham and Women's Hospital have developed a capsule that can deliver a week's worth of HIV drugs in a single dose. This advance could make it much easier for patients to adhere to the strict schedule ...
Jan 9, 2018
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(Medical Xpress)—It's a good news/bad news scenario: Researchers have made a new discovery about HIV that will redirect curative strategies toward latent reservoirs of HIV—that's the good news. The bad news is that they ...
(Medical Xpress)—Individuals with the natural ability to control HIV infection in the absence of treatment are referred to as elite controllers (ECs). Such individuals maintain undetectable viral loads less than 50 copies ...
Researchers from the University of Illinois have demonstrated the importance of cell-type-specific targeting in the treatment of HIV. Their study, published in the Proceedings of the National Academy of Sciences, is one of ...
May 13, 2024
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University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.
Mar 19, 2024
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Recent work from the laboratory of Elena Martinelli, Ph.D., MPH, professor of Medicine in the Division of Infectious Diseases and of Microbiology–Immunology, has discovered how inhibiting an immune cell singling pathway ...
Mar 7, 2024
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