Medical research

Using models, 3-D printing to study common heart defect

One of the most common congenital heart defects, coarctation of the aorta (CoA) is a narrowing of the main artery transporting blood from the heart to the rest of the body. It affects more than 1,600 newborns each year in ...

Cardiology

Genetic mutation linked to aortic dissection in the chest

Researchers at UmeƄ University in Sweden have discovered a genetic mutation that can cause dissection of the thoracic aorta, which is the body's main artery. The mutation leads to an impaired function of the smooth muscle ...

Cardiology

Pathological thickening of the cardiac wall halted

The heart responds to the increased stress caused by chronically raised blood pressure, for example, by thickening its wall muscle. In the late stage of this condition, a risk of heart failure arises. Scientists from the ...

Medical research

Dendritic cell subtype protects against atherosclerosis

Atherosclerosis, commonly referred to as "hardening of the arteries," is a major risk factor for heart attack and stroke. The cause of atherosclerosis is not well understood but, for some time, chronic inflammatory immune ...

Medical research

T cells key in atherosclerosis-linked inflammation

(HealthDay) -- In a mouse model of atherosclerosis, CD4+ T cells interact with antigen-presenting cells (APCs) in the presence of cognate antigen, leading to cell activation and proliferation and the secretion of proinflammatory ...

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