A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria—the brain's cellular power plants—can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative ...
Sep 14, 2015
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Scientists at the University of East Anglia (UEA) have discovered a 'constant cloud' of potent inflammatory molecules surrounding the cells responsible for diseases such as thickening of the arteries and rheumatoid arthritis.
Jul 4, 2012
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The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system. An imbalance of microbial metabolites has been implicated ...
Sep 20, 2021
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Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ...
Apr 10, 2020
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New research reveals the mechanism by which an experimental drug can protect the kidneys from sudden damage, called acute kidney injury (AKI). The findings, which appear in an upcoming issue of the Journal of the American ...
Jul 11, 2013
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(HealthDay)—Thioredoxin-interacting protein (TXNIP) blocks autophagic flux and induces expression of α-synuclein accumulation via inhibition of ATP13A2, according to a study published online July 29 in CNS Neuroscience ...
Aug 2, 2017
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A research group led by Associate Professor Naoko Inoue (she/her), doctoral student Safiullah Hazim (he/him), Associate Professor Yoshihisa Uenoyama (he/him), and Professor Hiroko Tsukamura (she/her) of the Graduate School ...
May 17, 2023
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Copper imbalances have been associated with a number of pathological conditions, including cancer. Publishing in PNAS scientists at EPFL have found that copper in drinking water – given at the maximum levels permitted in ...
Nov 14, 2013
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In the face of growing antibiotic resistance among bacterial infections, scientists at The Hospital for Sick Children (SickKids) have delved into the molecular science behind treatment-resistant tuberculosis.
Jun 28, 2023
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Researchers have long wondered how glial cells, which help provide nutrition and maintain the immediate environment around nerve cells, modulate the activity of nerve cells.
Feb 21, 2018
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