Diseases, Conditions, Syndromes

Kidney protein as potential target for treating autoimmune diseases

Approximately 23.5 million people in the U.S. have an autoimmune disease, and some studies suggest that number could be rising. New research using a mouse model for multiple sclerosis has uncovered a potential new area to ...

Diseases, Conditions, Syndromes

What may be behind the unexplained cases of hepatitis in kids?

Several countries, including the U.S., have identified or are investigating unexplained hepatitis cases in children. While the reported cases are appearing in clusters, they remain rare. About 200 children are affected worldwide.

Genetics

Exploring autoimmunity's regulatory roots

Our genome contains vast networks that regulate the activity of protein-coding genes. Variations in this regulatory DNA (which does not encode proteins) may affect both when and how much of a given protein a cell produces. ...

Diseases, Conditions, Syndromes

Virus might be behind mystery child hepatitis cases: US agency

Nine young children from Alabama affected by a mysterious hepatitis (inflammation of the liver) all tested positive for a common pathogen called adenovirus 41, a study by the US health agency said Friday.

Neuroscience

Findings open way for personalized multiple sclerosis treatment

Currently available therapies to treat multiple sclerosis (MS) lack precision and can lead to serious side effects. Researchers at Karolinska Institutet in Sweden have now developed a method for identifying the immune cells ...

Genetics

Scientists find a genetic cause of lupus

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

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Autoimmune disease

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body really attacks its own cells. This may be restricted to certain organs (e.g. in thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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