Medications

Peresolimab found to be efficacious for rheumatoid arthritis

Peresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patients with rheumatoid arthritis, according ...

Oncology & Cancer

T cells can activate themselves to fight tumors

When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that.

Immunology

Autoimmune disorders found to affect around 1 in 10 people

A new population-based study of 22 million people shows that autoimmune disorders now affect about 1 in 10 individuals. The work, published in The Lancet, also highlights important socioeconomic, seasonal, and regional differences ...

Diseases, Conditions, Syndromes

Researchers uncover new details on rare immune disease

In an 11-year study, researchers at the National Institutes of Health have further characterized idiopathic CD4 lymphocytopenia (ICL), a rare immune deficiency that leaves people vulnerable to infectious diseases, autoimmune ...

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Autoimmune disease

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body really attacks its own cells. This may be restricted to certain organs (e.g. in thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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