Medical research

Using 'organs-on-a-chip' to model complicated diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

Immunology

Scientists discover new 'Jekyll and Hyde' immune cell

Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with "Jekyll and Hyde properties". These cells play a key protective role in immunity to infection but—if unregulated—also mediate ...

Diabetes

A better diagnosis of rare diabetes to adapt treatment

Diabetes affects more than 400 million people worldwide and is a major public health problem. Although commonly referred to as a single disease, it actually constitutes a group of metabolic disorders with hyperglycaemia as ...

Immunology

Research pinpoints rogue cells at root of autoimmune disease

There are more than 100 different autoimmune diseases. But what unites them all is that they arise from an individual's own cells—rare and mysterious immune cells that target not external viruses and bacteria but the body's ...

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Autoimmune disease

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body really attacks its own cells. This may be restricted to certain organs (e.g. in thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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