Inflammatory disorders

Drug decreases gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the ...

Health

Celiac disease screening for family members

Celiac disease is an immune reaction to eating gluten. A recent Mayo Clinic study found that this autoimmune disease tends to run in families. Researchers say screening family members of celiac disease patients could prevent ...

Medical research

How self-reactive immune cells are allowed to develop

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1 cells are formed after that point. However, these cells are self-reactive—they ...

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Autoimmune disease

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body really attacks its own cells. This may be restricted to certain organs (e.g. in thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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