Diseases, Conditions, Syndromes

Withering away: How viral infection leads to cachexia

Many patients with chronic illnesses such as AIDS, cancer and autoimmune diseases suffer from an additional disease called cachexia. The complex, still poorly understood syndrome, with uncontrollable weight loss and shrinkage ...

Immunology

How stressed-out bacteria may trigger autoimmune response

Stressful life events most likely contribute to autoimmune diseases, but scientists don't have a deep understanding of the underlying chain of events. A study on mice published this week in mSystems suggests that the gut ...

Diseases, Conditions, Syndromes

Bone abnormalities in systemic autoimmune disease

An article published in Experimental Biology and Medicine details abnormalities in bone pathology that occur in systemic autoimmune disease. The study, led by Dr. Yasuhiro Kon, Professor in the Department of Basic Veterinary ...

Immunology

Rare disease gives new insight into regulatory T cell function

An international study led from Karolinska Institutet in Sweden provides new insights into the regulatory T cells' role in protecting against autoimmune disease. By mapping the targets of the immune system in patients with ...

Diabetes

How the body protects itself from type 2 diabetes

A specific group of white blood cells, termed "regulatory T cells," keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. Scientists at the German Center for Neurodegenerative ...

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Autoimmune disease

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body really attacks its own cells. This may be restricted to certain organs (e.g. in thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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