Genetics

It's not just what you eat, it's what's eating you

Restricting how much you eat without starving has been shown to robustly extend lifespan in more than 20 species of animals including primates. How this works is still unclear. In a new study published in PLOS Genetics, neuroscientists ...

Medical research

Scientists find rare disease clues in cell's recycling system

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular ...

Immunology

Communication between neighboring cells triggers autophagy

An immune-related protein deployed between neighboring cells in Drosophila plays an essential role in the cell degradation process known as autophagy, according to new research by Eric H. Baehrecke, PhD, at UMass Medical ...

Medical research

When a lack of sugar drives cells to eat themselves

Autophagy is the recycling process by which our cells keep themselves young. They continually break down and renew small parts of themselves in a kind of self-digestion; this helps to counteract harmful deposits which may ...

Immunology

New insights on how pathogens escape the immune system

The bacterium Salmonella enterica causes gastroenteritis in humans and is one of the leading causes of food-borne infectious diseases. During the infection, the germ is able to trick the immune system. Researchers led by ...

Medical research

Researchers find key to 'tired' blood and immune systems

A molecular key to aging of the blood and immune system has been discovered in new research conducted at UC San Francisco, raising hope that it may be possible to find a way to slow or reverse the growing risk for aging-associated ...

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