Diseases, Conditions, Syndromes

Autophagy—a review of techniques

In this comprehensive review with over 2,450 authors, the topics covered reflect the range of specialist fields within autophagy, and the diversity of animal, plant and fungal cell types that must inevitably invoke autophagy. ...

Immunology

Discovery reveals how protective immune cells protect themselves

Researchers at St. Jude Children's Research Hospital have discovered the mechanism by which immune cells called regulatory T cells keep themselves intact and functional during their demanding task of holding the immune system ...

Medical research

Autophagy research collaboration seeks answers to cell mystery

Researchers and students from Monash University and the University of Warwick have come together for the first time to share ideas, knowledge and expertise as part of a Monash Warwick Alliance seed funded autophagy workshop.

Medical research

Autophagy works in cell nucleus to guard against start of cancer

Autophagy, literally self-eating or the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting it plays a role ...

Medical research

Eye's recycling process key to seeing color, bright light

As many of us learned in high school science class, the retina's rods and cones allow us to see. Rods are for night vision, and cones operate in bright light and allow us to distinguish colors. But although scientists have ...

Oncology & Cancer

New drug squashes cancer's last-ditch efforts to survive

As a tumor grows, its cancerous cells ramp up an energy-harvesting process to support its hasty development. This process, called autophagy, is normally used by a cell to recycle damaged organelles and proteins, but is also ...

Immunology

Discovery provides insight into development of autoimmunity

Joslin researchers have uncovered the action of a gene that regulates the education of T cells, providing insight into how and why the immune system begins mistaking the body's own tissues for targets. The gene, Clec16a, ...

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