Medical research
Out of the limelight: Nobel medicine prize winner Ohsumi
Some people are drawn to the flashy and popular, but Nobel laureate Yoshinori Ohsumi isn't one of them.
Oct 3, 2016
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Page 14 - News tagged with autophagy
Medical research
Japan's Ohsumi wins Nobel for studies of cell 'self-eating' (Update 2)
Japanese biologist Yoshinori Ohsumi won the Nobel Prize in medicine on Monday for discoveries on how cells break down and recycle content, a garbage disposal system that scientists hope to harness in the fight against cancer, ...
Oct 3, 2016
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Oncology & Cancer
Scientists discover a specific molecular biomarker for malignant melanoma
Melanoma is one of the types of cancer that poses the greatest challenge to researchers because it manifests in many ways, it contains a large number of mutations and displays high metastatic capacity. To date, clinicians ...
Sep 7, 2016
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Medical research
Heart bypass without surgery?—AGGF1 induces therapeutic angiogenesis through autophagy
Coronary artery disease, the number one killer world-wide, restricts and ultimately blocks blood vessels, and cuts off oxygen supply to the heart. A study published on August 11 in the open access journal PLOS Biology reports ...
Aug 11, 2016
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Medical research
Autophagy under the microscope as never before
We don't tend to wrap our recycling waste in bubble wrap but that's essentially what cells do during the cellular recycling process called autophagy. Using the live imaging capabilities at the Babraham Institute, Institute ...
Aug 11, 2016
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Medical research
By inducing cellular autophagy, researchers prevent lung injury in mice
By triggering a process called autophagy—in which cells literally engulf their own insides —researchers from Drexel University and Yale University were able to decrease lung injury in mice that were exposed to high concentrations ...
Jul 19, 2016
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Genetics
Dietary restriction increases lifespan through effects on the gut
Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity in many species, including humans. A new study from the Sanford Burnham Prebys Medical Discovery Institute (SBP), published ...
Jul 14, 2016
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Medical research
Mechanism of autophagy initiation has just been revealed
In order to live, it is necessary for creatures not only to synthesize essential components, but also degrade harmful or superfluous components. Autophagy, an intracellular degradation system conserved among eukaryotes from ...
Jul 11, 2016
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Oncology & Cancer
Disrupting autophagy, a cellular housekeeping process, limits cancer spread
Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis ...
May 12, 2016
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Immunology
Defects in the body's cell disposal system may contribute to the most common form of lupus
A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude ...
Apr 20, 2016
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