Medical research

Autophagy works in cell nucleus to guard against start of cancer

Autophagy, literally self-eating or the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting it plays a role ...

Oncology & Cancer

Autophagy genes act as tumor suppressors in ovarian cancer

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina (MUSC) and University of California at San Diego (UCSD) published findings in PLOS Genetics this month showing that autophagy ...

Oncology & Cancer

Reversing pancreatic cancer's gluttony

In new findings published online March 18, 2021 in the journal Cancer Cell, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Moores Cancer Center, describe ...

Oncology & Cancer

Autophagy in dendritic cells helps anticancer activity

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell anticancer activity.

Inflammatory disorders

Specialized intestinal cells cause some cases of Crohn's disease

Scientists have discovered that Crohn's disease, the inflammatory bowel disorder, can originate from specialised intestinal cell type called Paneth cells. As such, they propose that small intestinal Crohn's disease might ...

Oncology & Cancer

New study points to a potential 'Achilles heel' in brain cancer

Scientists at Virginia Commonwealth University believe they have uncovered an "Achilles heel" of glioblastoma multiforme (GBM), the most common and deadly form of brain cancer. Their study published this week in the Proceedings ...

Immunology

Cellular self-digestion process triggers autoimmune disease

Autophagy refers to a fundamental recycling process of cells that occurs in yeast, fungi, plants, as well as animals and humans. This process allows cells to degrade their own components and thus activate energy resources ...

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