Flow of fluids through the gut, such as milk from an infant's diet, generates a shear stress on cells lining the intestine. Ken Lau, Ph.D., and colleagues have demonstrated that microvilli – finger-like membrane protrusions ...
Oct 27, 2017
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Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to ...
Sep 20, 2017
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Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful ...
Sep 7, 2017
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Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. ...
Aug 23, 2017
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Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular ...
Jul 17, 2017
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An immune-related protein deployed between neighboring cells in Drosophila plays an essential role in the cell degradation process known as autophagy, according to new research by Eric H. Baehrecke, PhD, at UMass Medical ...
Jun 29, 2017
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Two challenges in treating patients with estrogen-positive breast cancer (ER+) have been an inability to predict who will respond to standard therapies and adverse events leading to therapy discontinuation. A study at The ...
Jun 27, 2017
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Autophagy is the recycling process by which our cells keep themselves young. They continually break down and renew small parts of themselves in a kind of self-digestion; this helps to counteract harmful deposits which may ...
Jun 1, 2017
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The bacterium Salmonella enterica causes gastroenteritis in humans and is one of the leading causes of food-borne infectious diseases. During the infection, the germ is able to trick the immune system. Researchers led by ...
Mar 3, 2017
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Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas ...
Feb 23, 2017
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