New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons—thread-like projections that connect cells in the ...
Apr 20, 2017
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University of Louisville researchers have discovered that a protein previously known for its role in kidney function also plays a significant role in the nervous system. In an article featured in the April 13 issue of the ...
Apr 20, 2016
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During brain development, neurons extend projections called axons to connect with other neurons. Axons from groups of neurons with the same function tend to extend together, but the mechanisms involved in keeping the growing ...
Nov 21, 2014
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During brain development, nerve fibers grow and extend to form brain circuits. This growth is guided by molecular cues (Fig. 1), but exactly how these cues guide axon extension has been unclear. Takuro Tojima and colleagues ...
Aug 1, 2014
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Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular ...
Jul 20, 2012
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The complex inner wiring of the brain is coordinated in part by chemical guidance factors that help direct the interactions between individual neurons. As growing cells extend their axons outward, these tendrils are simultaneously ...
Aug 26, 2011
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BACE1 is the major drug target for Alzheimer's disease, but we know surprisingly little about its normal function in the CNS. Soraia Barão and Bart De Strooper (VIB/KU Leuven) now show that this protease is critically involved ...
Sep 14, 2015
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