Genetics

Genetic risk factor for premature birth found

Researchers at the University of California, San Diego School of Medicine have discovered a genetic risk factor for premature birth. The risk factor is related to a gene that codes for a protein that the scientists have found ...

Immunology

A new regulator of B cell development

Interleukin-33 (IL-33) drives inflammatory responses in allergic and nonallergic disease. Epithelial cells in the lungs, gastrointestinal tract and elsewhere release IL-33, which activates the ST2 receptor on immune cell ...

Oncology & Cancer

Attacking lymphoma at the source

Non-Hodgkin lymphomas are cancers that affect white blood cells of the immune system called B-lymphocytes, or B cells. Like cells in all cancers, the B cells begin to grow out of control, creating tumors in the lymph nodes, ...

Oncology & Cancer

Protein may represent a switch to turn off B cell lymphoma

Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...

Immunology

Rapid recall to fight familiar foes

The immune system's first encounter with a potential threat is a valuable learning experience. Through a process of genetic recombination, our immune B cells can potentially produce a wide array of B cell receptor (BCR) molecules, ...

Obstetrics & gynaecology

Researchers examine role of B cells in polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a common hormone disorder in women. Studies have shown that the change in hormones is accompanied by variations in immunological B cells. Researchers at Karolinska Institutet have now established ...

Oncology & Cancer

Advancing treatment for B-cell acute lymphoblastic leukemia

A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed ...

page 3 from 4