Patient-driven discovery reveals potential target for autoimmune diseases
A medical mystery served as the genesis for a Yale-led study that has promising implications for treating a range of autoimmune diseases.
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A medical mystery served as the genesis for a Yale-led study that has promising implications for treating a range of autoimmune diseases.
20 hours ago
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12
An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according ...
Jul 15, 2024
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Immune system dysregulation and elevated inflammation contribute to the development of the fatal neurodegenerative condition amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
Jul 11, 2024
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In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells in blood vessels ...
Jul 10, 2024
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CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy ...
Jul 10, 2024
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Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and the University of Bonn ...
Jul 8, 2024
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Many vaccines are only partially effective, have waning efficacy, or do not work well in the very young or the very old. For more than a decade, Ofer Levy, MD, Ph.D., and David Dowling, Ph.D., in the Precision Vaccines Program ...
Jul 3, 2024
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Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the realization of ePCs as therapies ...
Jul 2, 2024
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A research team including Professor Yoontae Lee and Jiho Park, a Ph.D. candidate, from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH) has discovered that a particular protein promotes ...
Jul 2, 2024
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B cells are known to generate antibodies through two different responses—an "emergency response" and an "everything is okay, let's prepare for the future response," says Mark Shlomchik, UPMC Professor and Distinguished ...
Jun 27, 2024
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B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response, which is governed by T cells). The principal functions of B cells are to make antibodies against antigens, perform the role of Antigen Presenting Cells (APCs) and eventually develop into memory B cells after activation by antigen interaction. B cells are an essential component of the adaptive immune system.
The abbreviation "B", in B cell, comes from the bursa of Fabricius in birds, where they mature. In mammals, immature B cells are formed in the bone marrow.
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