Scientists have discovered that the body's own natural killer cells can suppress the immune benefits of therapeutic vaccines, a problem that can affect inoculations against chronic viral infections and cancer.
Immunologists in Australia have eavesdropped on a stowaway population of B cells that hide in the lungs, their telltale biomarkers indicating they're armed to fight influenza—and their presence yet another sign that the ...
Numerous vaccines, from flu shots to those those that help thwart chickenpox and measles, are widely used to guard against contagion, but researchers in France are proposing a breakthrough role for rotavirus vaccines: deploying ...
A deeper understanding of the immune system's role in controlling cancer has helped drive "an immunotherapy revolution," offering hope for many patients with previously incurable cancers, including children, doctors have ...
Research led by the Department of Pathology at Stanford University, California, has found that chimeric antigen receptor T (CAR T) cell therapy can potentially result in a reactivation of human herpesvirus 6 (HHV-6) by CAR ...
Research led by the Université Paris Cité, CNRS, France, has investigated factors driving variability in diverse immune responses to SARS-CoV-2.
People with an impaired immune system can achieve a relatively robust response against SARS-CoV-2 if they get a booster shot, scientists in Sweden have found in a clinical trial that administered extra mRNA shots to patients ...
Immunology research led by Harvard Medical School has taken a closer look at the role of B-cells in fighting cancer. In a paper, "B-cell-specific checkpoint molecules that regulate anti-tumor immunity," published in Nature, ...
Three epidemic or pandemic coronaviruses—SARS-CoV, MERS-CoV, & SARS-CoV-2—have spilled over from animals to cause deadly illness in humans in the past 20 years. Virus researchers are determined to discover a means to ...
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No story in biology is more intriguing than the one involving B cells and the intricate processes that result in antibody production—it's a story about mathematics, a tale of genetics and a saga of how vast armies of tiny ...
B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response, which is governed by T cells). The principal functions of B cells are to make antibodies against antigens, perform the role of Antigen Presenting Cells (APCs) and eventually develop into memory B cells after activation by antigen interaction. B cells are an essential component of the adaptive immune system.
The abbreviation "B", in B cell, comes from the bursa of Fabricius in birds, where they mature. In mammals, immature B cells are formed in the bone marrow.
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