Medical research

Molecular switch for 'exhaustion mode' of immune cells discovered

Tumors and certain viral infections pose a challenge to the human body which the immune system typically fails to handle. In these diseases it switches to a hypofunctional state that prevents adequate protection. However, ...

Diseases, Conditions, Syndromes

Clues to building a better herpes vaccine

Efforts to develop an effective vaccine for genital herpes, a common sexually transmitted disease, have largely failed. In a new study published in Nature, Yale researchers explore why, and their findings could lead to a ...

Diseases, Conditions, Syndromes

Checkmate for hepatitis B viruses in the liver

Researchers at Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with researchers at the University Medical Center Hamburg-Eppendorf and the University Hospital Heidelberg, have for ...

Diabetes

Newly discovered immune cell linked to type 1 diabetes

In a discovery that might be likened to finding medicine's version of the Loch Ness monster, a research team from Johns Hopkins Medicine, IBM Research and four collaborating institutions is the first to document the existence ...

Neuroscience

AAN: Oral BTK inhibitor superior to placebo in multiple sclerosis

(HealthDay)—The selective Bruton's tyrosine kinase (BTK) inhibitor evobrutinib at a dose of 75 mg once daily is associated with fewer enhancing lesions during weeks 12 through 24 among patients with relapsing multiple sclerosis, ...

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B cell

B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response, which is governed by T cells). The principal functions of B cells are to make antibodies against antigens, perform the role of Antigen Presenting Cells (APCs) and eventually develop into memory B cells after activation by antigen interaction. B cells are an essential component of the adaptive immune system.

The abbreviation "B", in B cell, comes from the bursa of Fabricius in birds, where they mature. In mammals, immature B cells are formed in the bone marrow.

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