New research by scientists at the University of Chicago suggests a person's antibody response to influenza viruses is dramatically shaped by their pre-existing immunity, and that the quality of this response differs in individuals ...
Dec 11, 2020
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Mutations in proteins called histone H1, which help package DNA in chromosomes, are a frequent cause of lymphomas, according to a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and The Rockefeller ...
Dec 10, 2020
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Unlike so many other deadly viruses, HIV still lacks a vaccine. The virus—which continues to infect millions around the world—has proven especially tricky to prevent with conventional antibodies, in part because it evolves ...
Nov 19, 2020
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Immunotherapies have transformed the treatment of several types of cancer over the last decade. Yet they focus on reactivating one arm of the immune system: cytotoxic T cells, which sniff out and kill tumor cells.
Nov 19, 2020
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When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation ...
Nov 5, 2020
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The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally ...
Nov 4, 2020
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Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, ...
Oct 29, 2020
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The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch. Scientists have long suspected that the gut's immune system, in the ...
Oct 29, 2020
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WEHI researchers have used powerful 'single cell multi-omics' technologies to discover a previously unknown ancestor of T and B lymphocytes, which are critical components of our immune system.
Oct 19, 2020
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As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others.
Oct 6, 2020
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