Medical research

Research reveals potential treatments for deadly tropical disease

Melioidosis is a tropical disease that claims an estimated 90,000 lives worldwide each year. There is no vaccine, and current treatments are hampered by the ability of the bacterium that causes the disease to resist even ...

HIV & AIDS

New sequencing study provides insight into HIV vaccine protection

In a new study, scientists led by the U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research identified a transcriptional signature in B cells associated with protection from SIV or HIV infection ...

Genetics

Researchers redefine the footprint of viral vector gene therapy

Building on a track record of developing adeno-associated viral (AAV) vectors as a groundbreaking clinical tool for gene therapy and gene editing, Children's Hospital of Philadelphia (CHOP) researchers report a more sensitive ...

Diseases, Conditions, Syndromes

B cells off the rails early in lupus

New research on the autoimmune disease systemic lupus erythematosus (SLE) provides hints to the origins of the puzzling disorder. The results were published Monday in Nature Immunology.

Diseases, Conditions, Syndromes

Clues to building a better herpes vaccine

Efforts to develop an effective vaccine for genital herpes, a common sexually transmitted disease, have largely failed. In a new study published in Nature, Yale researchers explore why, and their findings could lead to a ...

Diabetes

Newly discovered immune cell linked to type 1 diabetes

In a discovery that might be likened to finding medicine's version of the Loch Ness monster, a research team from Johns Hopkins Medicine, IBM Research and four collaborating institutions is the first to document the existence ...

HIV & AIDS

New HIV vaccine strategy 'pumps' the immune system

A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small ...

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