Genetics

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells, known as B2 cells, produce antibodies in response to a pathogen or a vaccine, providing defense and immunity against infections. But a small ...

Diseases, Conditions, Syndromes

How B cells fight the COVID-19 virus

A study of antibody-producing B cells from patients who recovered from COVID-19 reveals a new cross-reactive antibody and what makes some B cells more effective at neutralizing the virus.

Medical research

Less is more for the next generation of CAR T cells

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't ...

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