Diseases, Conditions, Syndromes

What makes an mRNA vaccine so effective against severe COVID-19?

The first two vaccines created with mRNA vaccine technology—the Pfizer/BioNTech and Moderna COVID-19 vaccines—are arguably two of the most effective COVID vaccines developed to date. In clinical trials, both were more ...

Diseases, Conditions, Syndromes

Immune memory less durable after severe COVID-19, study suggests

Infection-fighting B cells retain better memory of the coronavirus spike protein in University Hospital patients who recover from less-severe cases of COVID-19 than in those recovering from severe COVID-19, a new study suggests. ...

Medications

Axicabtagene ciloleucel slows large B-cell lymphoma

(HealthDay)—For patients with refractory or relapsed large B-cell lymphoma, axicabtagene ciloleucel (axi-cel) leads to improvements in event-free survival and response compared with standard care, according to a study published ...

Immunology

How the immune system builds long-term memory

Experts in Japan have identified a fundamental part of the immune system's long-term memory, providing a useful new detail in the pursuit to design better vaccines for diseases, ranging from COVID-19 to malaria. The research, ...

Medications

New hope for patients with relapsed large B-cell lymphoma

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, ...

Oncology & Cancer

Thanks to clinical trials, big leaps made in lymphoma treatment

Newer therapies are outpacing the current treatment for diffuse large B cell lymphoma, according to data that scientists will deliver from two major clinical trials at the American Society of Hematology (ASH) annual meeting ...

Oncology & Cancer

Talk between immune cells could lead to new cancer vaccine

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune ...

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