To get the upper hand on the coronavirus, we first need to understand how our immune system reacts to it. Understanding this will lead to better treatments, effective vaccines and knowing how near we are to herd immunity—and ...
Jul 20, 2020
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Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic joint inflammation that leads to functional impairment in many sufferers. There are gender-specific differences in the emergence and development ...
Oct 21, 2022
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Parents tell their children to eat all the food on their plate, down to the last crumb. Certain cells within our lymph nodes, like obedient children, diligently follow this instruction. Although these cells—a subtype of ...
Jun 12, 2023
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Immunologist Frances Lund, Ph.D., and colleagues have detailed the role of a key controlling factor in the transformation of B cells into antibody-secreting cells, the cells that produce antibodies to fight invading pathogens ...
May 7, 2019
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Reproducing a rare type of B cell in the laboratory and infusing it back into the body may provide an effective treatment for severe autoimmune diseases such as multiple sclerosis or rheumatoid arthritis, according to researchers ...
Oct 14, 2012
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Mutations in proteins called histone H1, which help package DNA in chromosomes, are a frequent cause of lymphomas, according to a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and The Rockefeller ...
Dec 10, 2020
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Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors. The body has two ...
Jan 5, 2017
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In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) ...
Dec 10, 2017
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As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune response, increased ...
Feb 15, 2013
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The immune system's B cells have the unique distinction of being the only cells in the human body that evolve, in real time—and an international team of scientists announced in Nature Immunology that they have uncovered ...
May 25, 2021
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