Diabetes

Islet-released mediators impact transplant outcome

(HealthDay)—Cytokines and chemokines produced by pancreatic islets in response to inflammatory and metabolic stress include interferon gamma-induced protein 10 (IP-10/CXCL10), which is associated with poor islet transplant ...

Alzheimer's disease & dementia

Unraveling Alzheimer's: New study documents how brain cells go bad

In the brains of people with Alzheimer's disease, there are abnormal deposits of amyloid beta protein and tau protein, and swarms of activated immune cells. But scientists do not fully understand how these three major factors ...

Diabetes

What role does the gut play in type 2 diabetes?

In the destructive cycle that leads to and perpetuates type 2 diabetes, driven by overeating, excessive blood glucose, defective pancreatic beta cell function, and imbalances in insulin-regulating hormone levels, the gut ...

Alzheimer's disease & dementia

BACE-Inhibitor successfully tested in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments. ...

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