Beta cells in the pancreas are responsible for producing the vital hormone insulin. In diabetes, these cells are either destroyed or functionally impaired, resulting in elevated blood sugar levels in the body.
Aug 31, 2022
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A new study led by Associate Professor Ghada Soliman examines how the mechanistic target of Rapamycin (mTOR) protein regulates nutrient metabolism and glucose homeostasis in humans.
Aug 30, 2022
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Researchers at the Center for Genomic Regulation (CRG) have identified a DNA sequence that is crucial for pancreatic differentiation and function—and for the first time—describe how it works.
Aug 22, 2022
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Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce ...
Aug 10, 2022
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Although Aduhelm, a monoclonal antibody targeting amyloid beta (Aβ), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease Aβ plaque burden in AD patients, its effect ...
Aug 4, 2022
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Preeclampsia is a serious complication of pregnancy characterized by high blood pressure and kidney damage. Mayo Clinic researchers found that women with a history of severe preeclampsia have more markers linked to brain ...
Aug 3, 2022
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Alzheimer's disease can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery.
Jul 29, 2022
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In type 1 diabetes, the body develops immune cells that target pancreatic beta cells, which play a critical role in the production and secretion of insulin. One of the earliest targets of this immune response is a specific ...
Jul 25, 2022
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A world-first study by Monash University, in Melbourne, Australia has discovered a pathway to the regeneration of insulin in pancreatic stem cells, a major breakthrough toward new therapies to treat Type 1 and Type 2 diabetes.
Jul 22, 2022
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Physiologists at the Medical College of Wisconsin have identified the enzyme thioredoxin reductase as playing a key role in protecting beta cells from oxidative stress and in the regulation of insulin secretion.
Jul 14, 2022
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