Researchers at Weill Cornell Medicine have demonstrated how amyloid beta, a peptide associated with Alzheimer's disease, can interact with a protein receptor on immune cells in the brain. This triggers a reaction that damages ...
Nov 8, 2023
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A new study led by Associate Professor Ghada Soliman examines how the mechanistic target of Rapamycin (mTOR) protein regulates nutrient metabolism and glucose homeostasis in humans.
Aug 30, 2022
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Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce ...
Aug 10, 2022
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Physiologists at the Medical College of Wisconsin have identified the enzyme thioredoxin reductase as playing a key role in protecting beta cells from oxidative stress and in the regulation of insulin secretion.
Jul 14, 2022
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Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell ...
Dec 21, 2021
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A recent paper published in Frontiers in Neuroscience, outlines a pulse-pressure-induced pathway of cognitive decline that sheds light on why previous treatments for dementia may have failed and proposes promising new directions ...
Jun 24, 2020
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Sometimes the most complex problems actually have very simple solutions. A group of South Korean researchers reported an efficient and effective redox-based strategy for incorporating multiple functions into simple molecular ...
May 11, 2020
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Problems with insulin secretion experienced by people with Type 2 diabetes, parallel similar problems with insulin-secreting beta cells in many individuals with Down syndrome. A new study, published on May 19 in PLOS Genetics ...
May 19, 2016
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Blocking a key receptor in brain cells that is used by oxygen free radicals could play a major role in neutralizing the biological consequences of Alzheimer's disease, according to researchers at Temple University.
Nov 18, 2014
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Research published in the journal Nature Medicine on Monday by my team provides hope for a new approach to treating type 2 diabetes. In animal models of the disease, our treatment restores natural control of blood sugar.
Nov 6, 2014
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