Alzheimer's disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease ...
Sep 2, 2020
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Choline, an essential nutrient produced in small amounts in the liver and found in foods including eggs, broccoli, beans, meat and poultry, is a vital ingredient for human health. A new study explores how a deficiency of ...
Jan 17, 2023
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Among people with no memory or thinking problems, having a poor score on a simple memory test may be linked to biomarkers in the brain associated with Alzheimer's disease as well as very early signs of memory impairment that ...
Feb 23, 2022
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Sanford Burnham Prebys Medical Research Institute (SBP) researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins ...
Mar 7, 2018
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Although around one in 14 people over 65 have Alzheimer's disease, there's still no cure, and no way to prevent the disease from progressing. But a recent study may bring us one step closer to preventing Alzheimer's. The ...
Mar 8, 2021
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Losing the activity of a key ion channel in the brain may contribute to the buildup of a devastating and toxic protein responsible for the clumps of plaque that accumulate in Alzheimer's disease, a team of neurobiologists ...
As people age, a normal brain protein known as amyloid beta often starts to collect into harmful amyloid plaques in the brain. Such plaques can be the first step on the path to Alzheimer's dementia. When they form around ...
Feb 17, 2021
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New research published in Stem Cell Reports has found elevated cholesterol supply from astrocytes to neurons in the model of Alzheimer's disease (AD) brains, suggesting that modulating brain cholesterol could be explored ...
Aug 26, 2021
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An experimental study from Lund University in Sweden has revealed that the Alzheimer's protein amyloid-beta accumulates inside nerve cells, and that the misfolded protein may then spread from cell to cell via nerve fibers. ...
Aug 18, 2021
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An anti-inflammatory drug candidate, known as 3,6'-dithiopomalidomide (DP) and designed by researchers at the National Institute on Aging (NIA), protected lab mice against cognitive decline by reducing brain inflammation. ...
Mar 2, 2022
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