About half of all tumors are missing a gene called p53, which helps healthy cells prevent genetic mutations. Many of these tumors develop resistance to chemotherapy drugs that kill cells by damaging their DNA.
Oct 22, 2015
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113
A newly developed protein has successfully prevented dementia from occurring in lab mice carrying human Alzheimer's genes, raising the possibility for development of new treatments for the disease.
Oct 21, 2015
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143
Many bugs that make us sick—bacteria, viruses, fungi and parasites—hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles ...
Sep 28, 2015
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146
Researchers at Case Western Reserve University School of Dental Medicine have unraveled one of the mysteries of how a small group of immune cells work: That some inflammation-fighting immune cells may actually convert into ...
May 21, 2015
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Chewing, breathing, and other regular bodily functions that we undertake "without thinking" actually do require the involvement of our brain, but the question of how the brain programs such regular functions intrigues scientists.
May 14, 2015
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205
For decades, scientists and physicians have puzzled over the fact that infants with the postnatal neurodevelopmental disorder Rett syndrome show symptoms of the disorder from one to two years after birth.
Apr 13, 2015
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23
Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal ...
Mar 20, 2015
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87
Once HIV-1 has hijacked a host cell to make copies of its own RNA genome and viral proteins, it must assemble these components into new virus particles. The orchestration of this intricate assembly process falls to a viral ...
Feb 27, 2015
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6
A new study from MIT implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer. These proteins, known as Musashi proteins, can force cells into a state associated ...
Dec 15, 2014
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Ewing sarcoma is a cancer of bone or its surrounding soft tissue that primarily affects children and young adults. A hallmark of Ewing sarcoma is a translocation event that results in the fusion of an RNA binding protein, ...
Nov 17, 2014
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