Medical research

Cryo-EM imaging of STING protein reveals new binding pocket

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report ...

Medical research

Uncovering the HIV life cycle

Though it has been eclipsed lately by SARS-CoV-2, there is another global epidemic still threatening people: HIV/AIDS. According to UNAIDS, a United Nations initiative, some 38 million people worldwide are currently infected ...

Immunology

CRISPR screen identifies new anti-inflammatory drug target

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...

Arthritis & Rheumatism

Rheumatoid arthritis treated with implanted cells that release drug

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will ...

Medical research

Guppy research shows ADHD drugs can affect later generations

By studying guppies, scientists at the University of Toronto and Florida State University found that behaviors affected by methylphenidate hydrochloride (MPH) – the active ingredient in stimulants such as Ritalin and Concerta ...

Medical research

Study reveals neural stem cells age rapidly

In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi, Ph.D., demonstrates that neural stem cells—the stem cells of the nervous system—age rapidly.

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