Arthritis & Rheumatism

A deep-dive into the impact of arthritis drugs on gene expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present ...

Oncology & Cancer

Pushing MYC inhibition closer to the clinic

Cutting-edge sequencing technology has revolutionized cancer diagnosis and since identified several so-called cancer driver genomic aberrations. This has led to the development of an extensive and powerful arsenal of anti-cancer ...

Genetics

Genetic 'usual suspects' identified in researchers' new list

It's no secret that our genes are what makes us... us! But genes are often also the basis for debilitating diseases. One of the major clues to understanding any illness is seeing which genes are acting unusually during disease ...

Genetics

Are mosaic embryos the 'dark horse' of IVF?

Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percent of human embryos.

Genetics

Brain cells involved in insomnia identified

An international team of researchers has identified, for the first time, the cell types, areas and biological processes in the brain that mediate the genetic risk of insomnia. This was made possible by assessing DNA and sleep ...

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