Medical research

Central signaling response found in mitochondrial energy diseases

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat ...

Diseases, Conditions, Syndromes

Novel drug acts in unique way to protect against kidney injury

New research reveals the mechanism by which an experimental drug can protect the kidneys from sudden damage, called acute kidney injury (AKI). The findings, which appear in an upcoming issue of the Journal of the American ...

Neuroscience

From electronic brains to the power of the mind...

The EU budget has provided more than EUR 1.9 billion for brain research since the start of the current EU framework programme for research, FP7, in 2007. This has funded more than 1200 projects with more than 1500 participants ...

Neuroscience

Sugar solution makes tissues see-through

Japanese researchers have developed a new sugar and water-based solution that turns tissues transparent in just three days, without disrupting the shape and chemical nature of the samples. Combined with fluorescence microscopy, ...

Cardiology

Researchers identify 'master coordinator' for aortic rupture

Every year, more than 16,000 Americans die as a result of what's known as an "aortic dissection"—a catastrophic rupture of the aorta, the body's largest artery. Once thought to be a simple structural failure, aortic dissection ...

Neuroscience

Prying open the black box of the brain

The human brain is the most complex biological structure on Earth. It has about 100 billion neurons—each of which has thousands of connections to other neurons.

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

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