Medical research

Cell-cell signals in developing heart

During late stages of heart development, interactions between the endocardium (the inner layer of cells) and the myocardium (the heart muscle) are known to be crucial. Signaling between these two cell layers during the earliest ...

Pediatrics

First-ever in-utero surgery to treat spina bifida

A team of specialists at UPMC Magee-Womens Hospital and UPMC Children's Hospital of Pittsburgh have performed UPMC's first in-utero surgery to close an open neural tube defect in a baby months before her birth.

Diseases, Conditions, Syndromes

Rheumatoid arthritis drug diminishes Zika birth defects in mice

In experiments with pregnant mice infected with the Zika virus, Johns Hopkins Medicine researchers report they have successfully used a long-standing immunosuppressive drug to diminish the rate of fetal deaths and birth defects ...

Diseases, Conditions, Syndromes

Risk of congenital Zika syndrome greater than previously thought

Zika virus infection during pregnancy was first linked to birth defects during the outbreak in the Americas in 2015 and 2016; however, the Zika virus was discovered decades ago. Why then were adverse outcomes during pregnancy ...

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