Genetics

Final chapter to 60-year-old blood group mystery

Researchers have solved a 60-year-old mystery by identifying a gene that can cause rejection, kidney failure and even death in some blood transfusion patients. In this study, published in Nature Genetics online 7 April, they ...

Oncology & Cancer

Researchers reveal mechanism of drug reactivating tumor suppressors

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...

Oncology & Cancer

Unraveling predisposition in bilateral Wilms tumor

Children with bilateral Wilms tumor have a tumor in each of their kidneys—a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease. Scientists at St. Jude Children's Research ...

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