A precision-engineered gene therapy virus, inserted into blood stem cells that are then transplanted, markedly reduced sickle-induced red-cell damage in mice with sickle cell disease, researchers from Dana-Farber/Boston Children's ...
Sep 6, 2016
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Adult humans have many more blood-creating stem cells in their bone marrow than previously thought, ranging between 50,000 and 200,000 stem cells. Researchers from the Wellcome Sanger Institute and Wellcome—MRC Cambridge ...
Sep 5, 2018
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This week a team of scientists and physicians from the U.K. published news of a second HIV positive man, in London, who is in long-term (18-month) HIV remission after undergoing treatment for Hodgkins lymphoma. The unexpected ...
Mar 7, 2019
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Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, ...
Jun 23, 2016
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Using large-scale zebrafish drug-screening models, researchers at Boston Children's Hospital have identified a potent group of chemicals that helps bone marrow transplants engraft or "take." The findings, published in the ...
Jul 22, 2015
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Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – ...
Jan 17, 2013
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Finding a cure for a rare type of blood cancer could be accelerated by a new virtual platform that allows researchers easy access to data from patient samples generated by laboratories around the world.
Apr 27, 2017
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One of the biggest questions about the treatment of multiple myeloma, a form of blood cancer, is why nearly all patients treated with current therapies eventually suffer relapse. A Yale Cancer Center study may have solved ...
Dec 8, 2015
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A new approach pioneered at the University of Pennsylvania's Abramson Cancer Center may provide a new path towards treating Acute Myeloid Leukemia (AML) with CAR T cells. To treat AML, investigators have to target a specific ...
May 31, 2018
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When the immune system detects a foreign pathogen, a cascade of chemical signals call white blood cells to the scene. Neutrophils are the most common and abundant type of these cells and while they start accumulating at the ...
Dec 13, 2019
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