If a new anti-cancer drug shows promise in a Petri dish, often the next step is to test the drug's effect in mice. This system tends to work well with drugs that directly target cancer, but breaks down with immunotherapies. ...
Aug 23, 2018
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The mechanics behind how an important process within the cell traps material before recycling it has puzzled scientists for years. But Penn State researchers have gained new insight into how this process seals off waste, ...
Aug 15, 2018
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Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess ...
Aug 9, 2018
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Scientists at The University of Texas MD Anderson Cancer Center have engineered a system allowing microscopic monitoring and imaging of cancer that has spread to the bone in mice so they can better understand and develop ...
Aug 1, 2018
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In a study published in Nature Communications, a group of researchers led by Takahiro Kuchimaru and Shinae Kondoh of Tokyo Institute of Technology (Tokyo Tech) have proposed an improved mouse model that could revolutionize ...
Jul 31, 2018
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A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system.
Jul 18, 2018
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For the first time, a team of international researchers has mapped the family trees of cancer cells in acute myeloid leukaemia (AML) to understand how this blood cancer responds to a new drug, enasidenib. The work also explains ...
Jul 16, 2018
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The doctors who have spent years studying the case call it "a series of fortunate events." What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome ...
May 30, 2018
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New research, led by cancer biologists from the University of Bristol, has shown that bone marrow cells can protect cancer cells from a plant derived anti-cancer agent called Parthenolide.
May 28, 2018
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Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that comprises 1 percent of all new cancer cases and almost 2 percent of cancer deaths in the U.S. The five-year survival rate for the disease is less ...
Apr 25, 2018
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