Genetics

Another byproduct of aging: Hypermutations in the brain

Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...

Medical research

Zebrafish study reveals cause of altered human facial development

Some substances in medicines, household items and the environment are known to affect prenatal child development. In a study published in Toxicological Sciences, researchers tested the effects of five drugs (including caffeine ...

Medical research

Key regulator of bone development identified

Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes—a condition known as brachydactyly. The discovery was made by researchers at Penn State ...

Medical research

Severe flu risk as immune cells swap with age

Lung infections with the influenza virus or a coronavirus more frequently result in severe disease progression in older people. This is due to an excessive inflammatory reaction that causes damage to the lung tissue. The ...

Medical research

Bone hormone influences brain development and cognition

Researchers from Columbia University Medical Center (CUMC) have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions ...

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